GLOW Blend
GLOW Blend is a precision-formulated 70mg triple-peptide complex combining BPC-157, GHK-Cu, and TB-500 for comprehensive tissue repair research. By uniting three distinct mechanisms, it addresses sequential regenerative phases. BPC-157 primes the vascular microenvironment via VEGF signaling, GHK-Cu drives extracellular matrix and collagen synthesis, and TB-500 facilitates directional cell migration through actin modulation. This synergistic stack is designed for advanced protocols requiring simultaneous vascular, structural, and cellular repair.
This precision-formulated triple-peptide blend brings together three extensively studied tissue-repair compounds, each operating through distinct, non-overlapping molecular mechanisms. Each vial contains BPC-157 (10mg), GHK-Cu (50mg), and TB-500 (10mg), lyophilized together for consistent, reproducible dosing.
BPC-157 (Body Protection Compound-157) is a synthetic 15-amino acid pentadecapeptide (sequence GEPPPGKPADDAGLV; CAS 137525-51-0; MW 1419.5 g/mol) derived from human gastric juice. It demonstrates exceptional stability in acidic, enzyme-rich environments and consistently activates the VEGF/VEGFR2-Akt-eNOS angiogenic signaling axis, producing proangiogenic and cytoprotective effects across gastrointestinal, musculoskeletal, tendon/ligament, cardiovascular, and neurological injury models.
GHK-Cu is a naturally occurring copper-peptide complex (Gly-His-Lys + Cu2+; CAS 49557-75-7; MW 403.9 g/mol) that functions as a master regulator of extracellular matrix synthesis. In research applications, GHK-Cu stimulates collagen and elastin production, enhances glycosaminoglycan synthesis, and modulates MMP/TIMP balance for optimal matrix remodeling while exhibiting antioxidant and anti-fibrotic properties.
TB-500 is a synthetic 7-amino acid fragment (Ac-LKKTETQ-NH2; CAS 885340-08-9) of thymosin beta-4 that modulates G-actin to F-actin polymerization balance, enabling directional cell migration toward injury sites. In research models, TB-500 has demonstrated enhanced cell migration, reduced fibrotic scarring, and improved regeneration in cardiac, muscular, ocular, and dermal injury paradigms.
The scientific rationale is mechanistic complementarity: BPC-157 primes the vascular microenvironment through angiogenic signaling; GHK-Cu provides structural building blocks for extracellular matrix synthesis; TB-500 drives cytoskeletal mechanics for cell migration. Together they create a comprehensive regenerative cascade - vascular priming, matrix scaffolding, and cellular migration - in a single preparation.
| Compound | MW / Formula | CAS No. | Sequence / Structure | Receptor / Target |
|---|---|---|---|---|
| BPC-157 (10mg) | 1419.5 g/mol | 137525-51-0 | GEPPPGKPADDAGLV | VEGF/NO modulator |
| GHK-Cu (50mg) | 403.9 g/mol | 49557-75-7 | Gly-His-Lys + Cu2+ | MMP/collagen modulator |
| TB-500 (10mg) | ~1019 g/mol | 885340-08-9 | Ac-LKKTETQ-NH2 | Actin-binding fragment |
The following compounds operate through distinct, non-overlapping mechanisms that complement this product's research pathways. Each is independently available from the General Peptide catalog.
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